OncoGraph
Ask about cancer research links, search the data, and check original sources.
For research, not medical advice.
Ask a research question
Ask about a gene, drug, cancer, or variant. See an AI explanation with numbered links to the records it used.
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The answer uses a sample of published records. It may miss evidence or be wrong. Check the source links. Do not enter patient information. How answers work.
Browse the data
Enter a name to inspect its connections and original sources. Try “EGFR drugs” to search a relationship.
Try:
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Browse disease names in the snapshot
Download the data
Want to check the data yourself? Get the same saved data this site uses.
Download all data (ZIP)Download individual JSON files
More tools and details for researchers
Run locally with Ollama (requires setup).
Follow a drug evidence path
Pick a drug below, then use “Trace an evidence path” on its detail page. Direct drug–disease records and paths through genes remain separate.
Review variant evidence
Choose the tool that matches your question. Both use accepted CIViC records in the published snapshot.
Compare profiles across cancer types and therapies
See sensitivity, resistance, contradictory and other evidence separately. Counts are evidence items, not patients or independent studies.
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Check a variant claim or inspect an Evidence Tree
Enter an exact CIViC gene, variant or complete molecular profile name, and cancer name or DOID. Optionally add a therapy and choose the input scope to separate reported sensitivity and resistance. A profile-name match does not prove an individual variant's effect. FDA labels and CIViC Assertions are not integrated.
What's available, and where?
| Capability | GitHub Pages | Local database |
|---|---|---|
| Search entities and inspect source-backed relationships | Yes, published snapshot | Yes, Python and HTTP API |
| Compare accepted CIViC molecular profiles | Yes, published snapshot | Source records available after import |
| Evidence Tree by gene, variant/profile, disease | Browser search and JSON export | Python, HTTP API, local MCP |
| Check a variant–therapy evidence claim | Rule-based snapshot check and JSON export | Python, HTTP API, local MCP |
| Ask questions about recorded relationships | Source-backed matching, prompt copy, and optional Cloudflare AI explanation | Optional connection to your own Ollama on localhost |
| Live query endpoint or remote MCP hosted on Pages | No | Run and host separately |
| US FDA label and CIViC Assertion grading | Not integrated | Not integrated |
The public snapshot is bounded and can be older than upstream sources or a local import. Missing results do not prove that evidence does not exist. OncoKB and COSMIC are outbound lookups only, not imported data.
For agent integration, see the Evidence Tree contract, query API, and local MCP tools.
Dataset size and snapshot statistics
Imported sources and snapshot dates
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